The Barney Point home on Callide Crescent was engulfed in flames when emergency crews arrived on the scene about 9.30pm.

It took about two hours to bring the fire under control, a Queensland Fire and Emergency spokeswoman said.

One person was killed in the blaze.

Police said the other occupants of the house were accounted for, and were not at home during the fire.

Forensic officers will continue to examine the scene on Monday.

Anyone with information should contact Crime Stoppers on 1800 333 000.