Hayne has been omitted from the Prime Minister's XIII squad to take on PNG on September 24 in Port Moresby in another setback to his rugby league comeback.

Footage of Hayne partying with alleged Hells Angels gang member Chris Bloomfield has been referred to the NRL's integrity unit, although that incident didn't play any role in the cross-code star's snubbing.

However, his patchy form since returning to rugby league means he won't be one of the possible or probable Kangaroos contenders at National Football Stadium against the Kumuls.

Australian coach Mal Meninga told Fairfax Media last month that Hayne wasn't a realistic chance of breaking back into the national team unless he made an immediate impact with the Titans. While Hayne has showed flashes of his brilliant best - including kicking the winning field goal against the Wests Tigers - he is still taking time to adjust to the NRL following his stints in the NFL and sevens rugby.

Meninga's No.1 for the PNG clash will be James Tedesco, while fellow fullbacks Josh Dugan and Greg Inglis will be the centre pairings.

Mitchell Moses has been rewarded for his late-season form with the Tigers and will slot into the halves with Roosters No.7 Mitchell Pearce. It is a tremendous comeback for Pearce, who will attempt to position himself as the back-up halfback to Cooper Cronk for the tour of Europe. Pearce is now a chance of making his Test debut just months after his career was at the crossroads following his infamous Mad Monday incident.

Hayne's former Parramatta teammate Semi Radradra is also part of the side despite missing a portion of the season through injury.

"This is an outstanding squad," Meninga said.

"There are four representatives from the test match against New Zealand and on top of that, no less than 9 of the players were a part of Origin this year.

"The PNG tours are some of the most enjoyable trips I have been on, but they are no holiday when you run onto the field.

"The PNG boys play a tough and energetic brand of football and they will be well backed by a huge crowd, all willing the home team on.

"Whenever you get the chance to visit and play rugby league in Port Moresby, it's a special experience and this game will be no different."