Several businesses at the the Biggera Waters complex were badly damaged or destroyed, with one factory roof collapsing entirely and another partly falling in.

Businesses were evacuated as black smoke poured into the air and several premises were still off limits on Thursday morning.

It took 13 fire crews about two hours to contain the blaze, which broke out about 6pm.

It wasn't extinguished until about 11.30pm and flared up again overnight, with crews called back to the scene, a Queensland Fire and Emergency Services spokeswoman said.

The owner of badly damaged Galaxy Pools Interior told Nine News it was too late to do anything by the time he found out.

QFES Acting Chief Superintendent Megan Stiffler told the ABC it took more than 40 firefighters to fight the blaze.

"There was limited access due to the chemicals that were in the building so all the fire fighting was done from an external point of view," she said.

"We did have ability to get an aerial appliance at the back of the premises, which really helped with containing the fire."

A QFES spokeswoman said it was too early to say whether the fire was suspicious or not.

- with Amy Mitchell-Whittington

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