At least two people are dead and dozens injured after a shooting in Las Vegas, police have said.
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The incident occurred at at the Route 91 Harvest country music festival outside a Las Vegas casino hotel, sending people fleeing. Police are also investigating reports of shootings elsewhere in the city.
Danita Cohen, a spokeswoman for the University Medical Centre, said the hospital was evaluating the condition of "many patients" with gunshot wounds.
The Los Angeles Times, meanwhile, said police were investigating reports of a "suspicious device" outside the Luxor Hotel.
A burst of gunfire was heard during a performance by Jason Aldean, which several witnesses said appeared to come from an upper floor of the Mandalay Bay Resort and Casino.
Officer Aden Ocampo-Gomez said deputies were at the scene.
In terrifying footage, the sound of what appears to be bullets can be heard over music, which quickly cuts out, as people can be seen screaming and running for cover or lying on the ground.
Witnesses attending the festival reported "bullets flying everywhere" from "multiple shooters".
Police tweeted: 'We're investigating reports of an active shooter near/around Mandalay Bay Casino. Asking everyone to please avoid the area.'
Las Vegas police confirm that one suspect is down and urge people to avoid the strip.
A witness told NBC Las Vegas: "They were firing from somewhere high and they were unloading clip after clip after clip... [there are] multiple shooters, there has to be," he said.
"It was hundreds of shots."
An Australian witness staying at the Mandalay Bay hotel told CNN that there was mayhem following the sound of machine-gun fire.
"The initial gun shots were machine-gun fire," he said. "We knew it was chaos and mayhem because people were running out of everywhere."
He also described scenes of chaos when police came across a group of guests taking cover.
"We were tucked away, about 12 of us, in a carpark thing, and the Swat team came and said hands up," he said.
"We didn't know where the shooter is. We knew they were confused like we were. Police ushered us out".
Another witness said: "Police said run and we started running."
Mandalay Bay is located on the south end of the Vegas strip and across from McCarran International Airport.
There are reports that police have also been fired upon.
The New York Times is reporting that police are also at the Ali Baba Restaurant, about a 10-minute drive from Mandalay Bay, and are investigating reports of a shooting at the New York-New York Hotel and Casino.
A police officer is believed to be among a number of people who have been shot, according to scanner reports.
Flights in out of McCarran Airport have been stopped.
Firearms can generally be carried openly throughout Nevada, though carrying a loaded rifle or shotgun inside a vehicle or on or along a public road is illegal. Although North Las Vegas has an ordinance prohibiting open carry at county parks or in vehicles within city limits, the ordinance does not supersede state law.
More to come.