Around 38,000 Australians are reported missing each year, and many are found quickly, but more than 2,500 families live with the heartache of waiting for a long-term missing person to come home.

It's a agonising wait for many families who desperately hope that a piece of information from the public will be the key to finding their loved one.

James Hunter, known affectionately as 'Crackers', mysteriously disappeared while travelling through central NSW on the way to a mining job in Lightning Ridge in 2020.

He was last seen at a pharmacy in Dubbo on February 28, 2020, around a month before NSW plunged into COVID-19 lockdowns, and hasn't used his bank cards since.

After waiting for Mr Hunter to get in contact, his family reported him as missing in July 2021 and a search was launched by Orana Mid-West detectives.

His blue 2005 Toyota Hilux was found on a property he was working at in Mendooran in March 2022 and it was seized for forensic examination.

Police have continued to search for Mr Hunter. High-tech drones were used to capture high resolution images of Mendooran bushland on March 22 and 23 for analysis.

Mr Hunter, who was 52 when he disappeared, lived in the Newcastle suburb of Tighes Hill and travelled to Dubbo, Mendooran and Dunedoo regularly for work.

He was also known to visit Walgett and Lightning Ridge.

Mr Hunter is described as being Caucasian in appearance, about 175cm tall, of a medium build with brown hair and eyes.

Anyone who has information in relation to Mr Hunter's whereabouts is urged to contact Dubbo Police Station on 02 6883 1599 or Crime Stoppers on 1800 333 000.

Kathleen Harris was last seen at her NSW home in Huskisson, north of Jervis Bay by a friend about 9pm on May 31, 1999.

The precocious 15-year-old high school student had developed a friendship with a member of the Rebels Outlaw Motorcycle Gang Clinton Hanlon.

Ms Harris migrated from Costa Rica to Australia with her father but after meeting Mr Hanlon, a father of two, she moved onto his property adjacent to the bikie's clubhouse.

Rumours swirled about Ms Harris falling pregnant before she disappeared but despite investigating Mr Hanlon, deputy state coroner Derek Lee found no evidence to suggest the pair were in a romantic relationship.

Medical records submitted to a 2013 inquest found that Ms Harris said she had multiple sexual partners in the lead-up to her disappearance.

The 15-year-old had planned to meet friends the day after she was last seen but she never arrived.

Her personal belongings, including her purse and keys, were found at her home.

Police said they're treating her disappearance as suspicious and have not ruled out that Ms Harris may have been murdered.

A $100,000 reward is on offer to anyone with information regarding Ms Harris' whereabouts.

If you have information that may assist police to locate Ms Harris please call Crime Stoppers on 1800 333 000.

Warren Meyer is one of four experienced hikers to mysteriously disappear in Victoria's High Country in the past 15 years.

The 57-year-old and his wife Zee went to Healesville for an Easter holiday on March 23, 2008.

He planned to meet her and their friends for lunch after he completed a "very easy" 10 kilometres walk from Dom Dom Saddle picnic area in Fernshaw.

Mr Meyer was well-equipped with a whistle, matches, paper maps, a mobile phone, food and water before he set off at 7.45am.

But when he failed to return a search was launched by his wife and friends at 4pm.

His white Subaru Forester was found in the picnic area carpark and a phone signal showed he was near the walking track at 9.01am.

Mr Meyer's family think it is highly unlikely that he got lost because of the equipment he carried and his hiking abilities. He had recently walked difficult tracks in Nepal and Papua New Guinea.

A witness reported hearing a barrage of gunfire in the national park at 9.15am on the day Mr Meyer disappeared.

The witness investigated the area he heard shots and said he found a burnt out campsite and empty beer cans. However, no bullet shells were found.

Police also noted that a psychiatric patient had escaped from a nearby facility and the two men could have crossed paths.

A massive search scoured the area in the days after Mr Meyer disappeared but no trace of him or his belongings were found.

A coronial inquest found Mr Meyer had died but it couldn't determine his cause of death.

If you have information that may assist police to locate Mr Meyer please call Crime Stoppers on 1800 333 000.