The northern police region includes Cairns, Cassowary Coast, Tablelands, Mount Isa and Townsville.

Operation Tango Anaconda, which ran from March to June, focused on deterring drug driving offences through high visibility random drug testing.

Over the course of the operation, 21,787 tests were conducted with 3892 drug drivers detected.

Northern drivers were followed by about one in five drivers testing positive in the southern region, which encompasses the Darling Downs, Ipswich, Charleville, Dalby-Burnett, Longreach, Roma and Pine Rivers.

About one in six drivers intercepted in the Brisbane region tested positive, and about one in six tested positive in the south eastern region, which includes Gold Coast and Logan.

The lowest rate of drug driving offences was detected in the central police region, with about one in seven testing positive to drugs. Central includes Bundaberg, Gladstone, Gympie, Mackay, Maryborough, Rockhampton and Sunshine Coast.

It is unclear how many tests were done in each police region.

Acting Inspector Paul Algie said it was disappointing to see this behaviour.

"It's disappointing that there are people out there who think it's acceptable to be out on our roads while they are under the influence of illicit drugs," Acting Insp Algie said.

"The consequences of drug driving are very serious. In the past decade we have seen around a 50 per cent increase in drug presence in fatal crashes and we know drugs are a major causal factor in 10 per cent of crashes Australia-wide."

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