Saville exited with a 7-5 3-6 7-5 first-round loss to Bulgaria's Viktoriya Tomova on Tuesday.

The 29-year-old had successfully pleaded with All England Club officials to hand her the last of seven wildcards into the women's main draw following a form resurgence in 2022 after finally overcoming a chronic foot injury.

Alas, Saville joined qualifiers Maddison Inglis, Zoe Hives and Astra Sharma in failing to clear the first hurdle.

She did put up a stand, though, refusing to throw in the towel after jarring her right knee in the sixth game of the deciding set and falling 5-2 behind.

But after clawing back to 5-5, Saville again dropped serve to stay in the set - as she did in the first set - to hand Tomova victory.

Hives' inspired Wimbledon campaign ended earlier on Tuesday with a gallant loss to Greek Maria Sakkari.

On the comeback trail following a lengthy battle with debilitating Postural Orthostatic Tachycardia Syndrome, Hives earned her way into the main draw with three qualifying wins at Roehampton.

But Sakkari proved a bridge too far, taking out the 26-year-old 6-1 6-4 in 78 minutes.

True to her character, Hives also put up up a fight, staging a mini comeback from 5-2 down in the second set to extend Monday's match.

But she eventually succumbed to the world No.5 on Court 3.

Ranked No.571 in the world after being unable to play for more than two years while fighting chronic fatigue, Hives' consolation is a career pay day of Stg 50,000 ($A88,000).

"It'll make a lot of difference to me," said the Ballarat battler.

"The Aussie Open money I earned a few years ago is still helping me. I can afford to get people to help me with other things, more time with my coach.

"I always promised myself if I got to main draw again I'd get myself a new car.

"But that now feels like an extravagance so I don't know if it's going to happen.

"But I'd like to! My old car goes up the hill and I'm going 'come on! ...

"I haven't decided yet - I'll wait until I get home."

Sharma's appearance in the main draw was also short-lived, with the West Australian losing her rain-delayed first-round match with Tatjana Maria 4-6 6-3 6-4.

The match was suspended under fading light at one set apiece on Monday night before the German nabbed the deciding set on Tuesday.

The departures of Saville, Hives and Sharma followed Inglis's exit on Monday with a 5-7 6-3 6-4 loss to Dalma Galfi.

Australian No.1 Ajla Tomljanovic also plays on day two, up against Swiss southpaw Jil Teichmann, the 18th seed.

And Jaimee Fourlis, the last of the Aussie qualifiers, plays Kirsten Flipkens.

Australian Associated Press